Poster Abstracts

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Number	Presenter	Title	PI
83	Brandon Iwaniec	Investigating functions outside of tRNA for a bacterial 3'-5' reverse polymerase from the Thg1/TLP superfamily	Jane Jackman
79	Christopher Cotter	Sleep Fragmentation Compromises Sleep Recovery Patterns Following Traumatic Brain Injury	Olga Kokiko-Cochran
73	Tyler Billings	A secondary structure transition stabilizes an auto-inhibited conformation in the apo Cre catalytic domain	Mark P. Foster
13	Cameron Ford	Acid Sensing Ion Channel 1a and Mitochondrial Function	Candice Askwith
42	Natasha Maria James	Adipose tissue plasticity in response to early pathological stress on the heart and mediation by adipose thermogenic activation	Kristin Stanford
39	Yi-Hui Wang	An AT-hook transcription factor promotes transcription of piRNA, histone and spliced-leader gene clusters	Wen Tang
33	Fawwaz Naeem	Analysis of programmed frameshifting during translation of prfB in Flavobacterium johnsoniae	Kurt Fredrick
111	Zhangfei Shen	Assembly and activation mechanism of the SIR2-HerA anti-phage defense system	Tianmin Fu
43	Bryan Perez Soto	Assessment of covalent labeling experiments via computational methods	Steffen Lindert
61	Kristin Chesnutt	ATAC and SAGA histone acetyltransferase modules facilitate transcription factor binding to nucleosomes in an acetylation independent manner	Michael G. Poirier
27	Jaylen Taylor	Bile Inhibits Bacterial Toxin Activity by Instigating Structural Destabilization and Oxidation	Dmitri Kudryashov
101	Yin Wei	Building DNA nanodevice to study DNA-binding protein affinity on curved DNA	Carlos Castro
34	Jessica Wedig	CD200 is overexpressed in the pancreatic tumor microenvironment and predictive of overall survival.	Thomas Mace
77	Morgan Bauer	Characterization of bi-allelic point mutations in human EPRS that are linked to neurological disease	Karin Musier-Forsyth
32	Lily Schumacher	Characterizing structural differences between plant KASH proteins and determining their functional contributions	Iris Meier
29	Courtney Dye	Chronic peripartum opioid exposure increases neuroinflammation and reduces maternal care in female rats	Kathryn M. Lenz and Benedetta Leuner
1	Nicklaus Halloy	Circadian Timing in PS19 Mouse Model of Tau Pathology	Karl Obrietan
36	Yonaida Valentine	Circulating CCL2 may be central to gut microbiota-mediated neuroinflammation and low emotionality after chemotherapy.	Leah Pyter Ph.D.
102	Rodrigo Muzquiz	Combined use of Solid-State and Solution NMR to Understand Allosteric Transitions in a Ligand-Activated Oligomeric Protein	Mark Foster
63	Matthew Benedek	Conformational heterogeneity influences recombination outcomes in the Cre-loxP system	Mark Foster
89	Lynde Wangler	CXCR2 antagonism shifted peripheral immune cell recruitment and activation towards regenerative phenotypes following diffuse TBI in mice	Jonathan Godbout Andrew Sas
49	Emily Chan	Deciphering Cell Polarity Through Clathrin-Mediated Endocytosis and its Implications for Breast Cancer Cell Migration	Comert Kural and Jonathan Song
40	Paul Russell	Deciphering mechanisms of ribosome turnover during global inhibition of translation elongation in mammalian cells	Michael G. Kearse
51	Wantong Li	Decoding transcription factor dependent enhancer-gene regulatory networks that define hematopoietic niche function.	Bradley W. Blaser
11	Bradley Cutler	Determining the functional conservation of prostaglandin E2 signaling in zebrafish behavioral fever	Martin Haesemeyer
118	Katelyn Amstutz	Determining the role of a plant LINC complex in stomatal closure	Iris Meier
62	Meretta Hanson	Development of differential sublaminar feedforward inhibitory circuits in CA1 hippocampus requires Satb2	Jason C. Wester
69	Chetan Gomatam	Direct effects of mineralocorticoid receptor signaling on dystrophic skeletal muscle fibroblasts	Jill A. Rafael-Fortney
88	Jonathan Montgomery	Dynamic Conformational Changes Modulate Interactions between Cre Recombinase and DNA Substrates	Mark Foster
97	Christian ONeil	Dynamic nuclear polarization of GB1 protein by co-crystallization with partial doping	Dr. Chris P. Jaroniec
5	Narayanan Puthillathu Vasudevan	Dynamics of K-Ras G12D inhibition	Rafael Bruschweiler
117	Delia Calderon	Elucidating the Role of ARF6 in Infantile Rhabdomyosarcoma	Genevieve Kendall
92	Junyan Yu	Engineering extracellular vesicles for targeted delivery of neurofibromatosis type 1 gene therapy	Daniel Gallego-Perez
120	Emma Woodward	Estradiol binding prefrontal ERB during puberty mediates the maturation of stress sensitivity in female mice	Laurence Coutellier
25	Jocelyn Treneff	Title not published online	Craig Burd
23	Paul Toth	Title not published online	Steffen Lindert
104	Moulisubhro Datta	Exploring the role of a tRNA SNP in the molecular basis of dextrocardia, a laterality disorder	Venkat Gopalan
9	Eleanor Rimmerman	Title not published online	Mitchel R. Stacy
119	Wolfgang Pfeifer	From Waste to Wonder: Recycling DNA for Eco-Friendly Nanostructure Fabrication	Carlos Castro
85	Joseph Beljan	Full-length dystrophin restoration in multiple patient cell lines with DMD pseudoexons using AAV-delivered U7snRNA	Kevin Flanigan
80	Dale Lingo	Functional investigation of Histoplasma capsulatum chitinases	Chad Rappleye
71	Mia Kordowski	Functionalized engineered extracellular vesicles for targeted delivery to intervertebral disc cells	Natalia Higuita-Castro
60	Ileanexis Rosado-Burgos	Glutamate induces proliferation of adult hippocampal neural stem cells through its metabolism	Liz D. Kirby
109	Salma B. Abdelbaky	Identification of biological components and novel clinical subsets of NPM1-mutated AML using an integrated, multi-omics approach	Christopher Oakes
7	Midhun Anne	Identification of distinct neuronal populations underlying motor impairment in a mouse model of SCN8A epileptic encephalopathy	Jacy L. Wagnon
90	Kaarthik Abhinav Balakrishnan	Identifying internal states that underlie thermal navigation behavior in larval zebrafish using Hidden Markov models and in-vivo functional imaging	Martin Haesemeyer
55	Joe Caporale	IL-2 Secreting NK Cells: Investigation of how differential expansion leads to an unfamiliar NK cell capability	Dean A. Lee
81	Benedict Hui	Impact of the high flexibility of the cadherin-catenin-vinculin complex on F-actin attachment	Xiaolin Cheng
31	Jonathan Packer	Impaired Cortical Neuronal Homeostasis and Cognition after Diffuse Traumatic Brain Injury Are Dependent on Phosphatase and Tensin Homolog and the PI3k-AKT Pathway	Jonathan P Godbout
8	Yinchong Wang	Improving CDK4/6i efficacy by combining it with NK cell therapy in breast cancer	Anna E. Vilgelm
50	Kai Jin	In vitro and In vivo Evaluation of the Pathology and Safety Aspects of RNA-Drug Conjugates in Cancer Therapies	Dr. Peixuan Guo
91	Monica Pan	Inhibition and Degradation of Mutant K-Ras with Cell-Permeable Proteins	Dehua Pei
68	Jack Kucinski	Initial rhabdomyosarcoma fusion-oncogene activity pioneers a distinct oncogenic signature in vivo	Genevieve Kendall
54	Daisy Alvarado	Title not published online	Vladislav Belyy
82	Lindsay Strehle	Investigating mammary tumor-induced effects on brain endothelial cells	Leah Pyter
108	Ian Price	Title not published online	Wen Tang
56	Reid Gohmann	Investigating virulence of AvrE1 in isolation of other type III effectors	David Mackey
67	Olivia Roumaya	Investigation of a unique vertebrate tRNA modification by Trmt10b in zebrafish	Jane Jackman
47	Abhjeet Bhullar	Title not published online	Peixuan Guo
99	Kristina Sattler	Med12 inactivation in myogenic progenitors impairs skeletal muscle differentiation	Christoph Lepper
14	Bryan Alvarez	Memory Impairments, Neuroinflammation, and Mitochondria Dysfunction in Aged Female Rats via Post-Surgical Morphine	Ruth Barrientos
15	Carlos Owusu-Ansah	Title not published online	Matthew Sullivan
30	Konur Oyman	Modeling Gilteritinib Resistance by Enforced cxcl8a Expression in Zebrafish HSPCs	Bradley W. Blaser
76	Amir Yousif	Modulating the epigenetic crosstalk to rescue responsiveness of dysfunctional CD8 T cells to immune checkpoint blockade	Hazem Ghoneim
53	Gianni Giarrano	Modulating the PI3K/Akt1 Kinase Pathway Increases Skeletal Muscle Plasma Membrane Repair in Muscular Dystrophy Models.	Noah Weisleder
112	Shridhar Sanghvi	Title not published online	Harpreet Singh
75	Blanche Chen	Natural nucleosome positioning sequences reveal induced nucleosome sliding by pioneer transcription factors.	Michael G. Poirier
59	Jake Willows	Title not published online	Kristy Townsend
44	Antonia Duran	NMR-based structure determination of the tRNA trans-editing enzyme ProXp-ala	Mark P. Foster
105	Wenfang Liu	Novel P-body like foci: the cellular site of tubulin autoregulation?	Paul Herman
26	Rachel Lew	NRAS mutation-specific properties of pan-RAF inhibitors	Christin Burd
2	Zhenyu Wu	NSUN1/2-mediated RNA m5C modification controls KSHV viral infection via regulating RNA stability of host restriction factors	Jian Zhu Netty G. Santoso
86	Kubra B. Akkaya	Title not published online	Maria M. Mihaylova
41	Xiaoyuan Yang	Oligomerization-mediated activation of a short prokaryotic Argonaute	Tianmin Fu
65	Jade Blackwell	Post-operative cognitive dysfunction is exacerbated in a model of alzheimer’s disease	Dr. Ruth M. Barrientos
58	Puyi Ma	Predicting protein flexibility with AlphaFold	Rafael Bruschweiler
37	Branden Verosky	Prenatal stress impairs placental immune function	Tamar Gur M.D. Ph.D
52	Ana Leon-Rodriguez	Primed microglia and increased hypothalamic neuroinflammation after acute stress in traumatic brain injured-mice	Jonathan Godbout
94	Motilal Uttarkabat	Probing µs-ms dynamics of histone proteins in chromatin by magnetic resonance spectroscopy	Christopher Jaroniec
113	Md. Siddik Alom	Title not published online	Kurt L. Fredrick
74	Elijah Day	Protein structure prediction with covalent labeling-mass spectrometry and machine learning	Steffen Lindert
48	Yi Wang	Title not published online	Zihai Li
93	Lex Tallan	Quantitative and Epigenetic Comparisons of Driver Fusions in a Childhood Sarcoma	Benjamin Stanton
78	Will Higgins	Quasi-Ordered Recognition Dynamics in Sperm-Egg Interactions in Abalone	Damien B. Wilburn
121	Enrique Ruiz	Rapid in vitro release of ssDNA from complex templates	Carlos Castro
110	Sabat Gonzalez-Serrano	Rationale protein engineering approach to accelerate a self-removing purification tag	David W. Wood
24	Chung-Ju Yeh	Regulation of satellite cell pool maintenance by FGFR1 and FGFR4	Christoph Lepper
66	Mahfam Shariati	Title not published online	Karin Musier-Forsyth
84	Sepideh Fakhretaha Aval	Role of the sarcin-ricin loop (SRL) of 23S rRNA in assembly of the 50S ribosomal subunit	Kurt Fredrick
3	Julia Faraone	SARS-CoV-2 spike mutation I692V drives destabilization of spike and attenuates viral infectivity	Shan-Lu Liu
100	Harper Smith	Searching for Biologically Relevant Protein-Protein Interfaces Using AlphaFold2	Marcos Sotomayor
103	Christina Budding	Site-specific identification and role of m6A RNA modification in HIV-1 genomic RNA 5'UTR	Karin Musier-Forsyth
28	Christopher Vadala	Spinal cord injury impairs wound healing through impaired resolution of inflammation in pressure ulcers	Jan Schwab
64	Anthony Alfredo	Spinal cord injury increases visceral adipose tissue inflammation and lipolysis	Dana McTigue
57	Rocio Zaldivar	SRPK1 interacts with the HTLV-1 hbz mRNA and influences cellular proliferation	Amanda Panfil
70	Samuel Houle	Stress Exposure Following Traumatic Brain Injury Dampens Acute Inflammatory Gene Transcription	Olga Kokiko-Cochran
21	Hsiang-Ling Huang	Structural insights into membrane repair protein dysferlin and dysferlinopathies	Krishna Chinthalapudi
115	Jenna Thuma	Title not published online	Jonathan Davis
12	Grace Johnecheck	Substrate Recognition by Two 3' to 5' RNA Polymerases in Dictyostelium discoideum	Jane E. Jackman
10	Thaanya Amarasekara	Substrate specificity and 3'-5'-polymerization capabilities of two tRNAHis guanylyltransferase-like proteins	Dr. Jane Jackman
72	Jacelyn Greenwald	Surface proteomics to identify therapeutic targets in extracellular vesicles from Alzheimer's disease donors	Vicki Wysocki
46	Tianyi Tao	Telomerase Reverse Transcriptase (TERT) as a putative quiescent stem cell marker in the adult mouse hypothalamus that is responsive to caloric restriction and aging	Kristy Townsend
106	Ezgi Elmas	Title not published online	Dean A. Lee
96	Zachary Smith	The Effect of FT Transient Length on Measured SID Product Ion Intensities	Vicki H Wysocki
4	Zhiyuan Meng	The occupancy of Cbf1/Pho4 at different positions within the nucleosome entry-exit region	Michael Poirier
87	Nikaela Losievski	The role of Srp54 in motor neuron development in zebrafish and implications for spinal muscular atrophy	Stephen J. Kolb
20	Shrijan Khanal	Title not published online	Andrew J. Gunderson
45	Parth Pardeshi	Time-dependent analysis of Brown Adipose Tissue Extracellular Vesicles	Dr Kristin I. Stanford
6	Paige Bowling	Title not published online	John M. Herbert
35	Emily Ringwalt	Trabectedin Enhances Oncolytic Virotherapy Intratumoral Spread and Antitumor Immune Activation in Pediatric Bone Sarcoma Models	Ryan D. Roberts and Timothy P. Cripe
18	Joseph Holbrook	Tracking drugs and lipids: quantitative mass spectrometry imaging of liposomal doxorubicin delivery and bilayer fate in three-dimensional tumor models	Amanda B. Hummon
95	Gongbo Guo	TSC Patient-derived Pericytes and Endothelial Cells show Dysfunctional Molecular and Functional Phenotypes Using In vitro Blood-brain barrier model	Mark E. Hester
19	Caden Martin	Title not published online	Mark Parthun
107	Gargi Mishra	Title not published online	Kristy L. Townsend
38	Rakeb Tafesse	Title not published online	Natarajan Muthusamy
16	Yogesh Budhathoki	Unraveling Osteosarcoma Complexity: Constructing a Specialized Single-Cell Atlas for Accurate and Reliable Cell Type Annotation	Ryan D. Roberts
22	Jon Fritz	Visualizing AnxA2-driven active membrane repair dynamics in alveolar type I cells	Joshua A. Englert
17	Athena L. Biggs	When 'Believe in Yourself' Isn't Enough: Increased Ambivalence during Self-evaluation in Depression	Jay C. Fournier
98	Philip Kauffman	Title not published online	Ross Dalbey
114	Tong Xiao	ZFP148 represses effector differentiation and cytotoxicity of CD8+ T cells during chronic viral infection and cancer	Zihai Li
116	Calli Bellinger	Zymosan-stimulated neutrophils suppress T cell proliferation and ameliorate CNS autoimmune disease	Benjamin Segal