Poster abstracts

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Number Presenter Title PI
1Tong Xiao
Novel mechanisms of androgen receptor-centered transcriptional regulatory network in regulating CD8+ T cell exhaustion and sex bias in cancer Zihai Li
2Ariel Robbins
Cooperative control of a DNA origami force probe Michael Poirier
3Rakeb Tafesse
Understanding the role of EGFL7 in HSC precursors during HSC specification in the AGM Adrienne M. Dorrance
4Rory Chia-Ching Chien
Mechanism of Action of An in vivo Virulence Factor of Ehrlichia Yasuko Rikihisa
5Pablo Vidal Souza
Exercise-induced Adaptations to White Adipose Tissue Stromal Vascular Fraction Kristin I. Stanford
6Yi Wang
Title not published online Zihai Li
7Joe Beljan
Restoration of full-length dystrophin using AAV-delivered U7snRNA in patient cells with a DMD pseudoexon: a model for bespoke gene therapies in an orphan mutational class Kevin Flanigan
9Delia Calderon
VGLL2-NCOA2 leverages developmental programs for pediatric sarcomagenesis James F. Amatruda and Genevieve C. Kendall
10Shrijan Khanal
Title not published online Ramiro Garzon
11Kaitlyn Kray
Development of a gene therapy to permanently alter SMN2 to function like SMN1 Arthur H.M. Burghes
12Casey Beard
Sarcomere generation is localized to intercalated disc and dependent on local protein synthesis in cardiac hypertrophy Sandor Gyorke
13Ben Koff
Towards a structural understanding of Duchenne Muscular Dystrophy Krishna Chinthalapudi
14Andrew Savidge
Title not published online Kotaro Nakanishi
15Hsiang-Ling Huang
Title not published online Krishna Chinthalapudi
17Antonia Duran
NMR-based structure determination of the tRNA trans-editing enzyme ProXp-ala Mark P. Foster
18Tyler Billings
Cre recombinase adopts an auto-inhibited state enabled by an α-β secondary structure transition Mark P. Foster
19Christian ONeil
Determination of protofilament composition in amyloid fibrils by scanning transmission electron microscopy Dr. Christopher P. Jaroniec
20Daisy Alvarado
Validating AlphaFold 2 Models of an Heterophilic Adhesion Complex formed by Two Cadherins Important for Intestinal Epithelium Function Marcos Sotomayor
21Wei-Hsiang Weng
Molecular Mechanisms Underlying CIB-mediated TMC Activation in Inner-ear Mechanotransduction Marcos Sotomayor
22Annie Ashraf
Crystal Structure of the Membrane-Adjacent Domain of Cadherin-23, a Protein Essential for Hearing. Marcos Sotomayor
23Rodrigo Muzquiz
ombined use of Solid-State and Solution NMR to Understand Allosteric Transitions in a Ligand-Activated Oligomeric Protein Mark Foster
24Caden Martin
Regulation of Constitutive Heterochromatin by Histone Acetyltransferase 1 Mark Parthun
25Madhoolika Bisht
CRISPR-based live cell imaging reveals multi-tier chromosome territory deformation in Interphase nuclei Li-Chun Tu
26Shridhar Sanghvi
Title not published online Harpreet Singh
27Bryan Gemler
Ribosomes Lacking bS21 Gain Function to Regulate Protein Synthesis in Flavobacterium johnsoniae Ralf Bundschuh
28Kubra Akkaya
Title not published online Maria M. Mihaylova
29Wenfang Liu
Novel P-body like foci: the cellular site of tubulin autoregulation? Paul Herman
30Reid Gohmann
Contribution of putative target receptor-like kinases to AvrE-mediated virulence David Mackey
31Katelyn Amstutz
Determining the role of a plant LINC complex in stomatal closure Iris Meier
32Chung-Ju Yeh
Regulation of satellite cell pool maintenance by FGFR1 and FGFR4 Christoph Lepper
33Isabella Mendes
A pollen expressed kinesin-4 in Arabidopsis thaliana pollen tubes assists in male germ unit trafficking and is required for full seed set Iris Meier
34Manu Sanjeev
PYM1-mediated EJC destabilization limits non-canonical EJCs and controls expression of membrane-targeted mRNAs Guramrit Singh
35Hari Krishnan Balasubramanian
Active mitochondrial fission during fungal biofilm formation Stephen A Osmani
36Christopher Gilbert
Title not published online Federica Accornero
37Brian Scarpitti
Single particle imaging to monitor subcellular delivery of gold nanoparticles Zachary D. Schultz
38Elakkiya Tamilselvan
Title not published online Marcos Sotomayor
39Will Higgins
Investigating mutant hydrophobic patch exposure in troponin C using molecular dynamics-based free energy methods Steffen Lindert
40Puyi Ma
Predicting protein flexibility with AlphaFold Rafael Bruschweiler
41Salma B. Abdelbaky
Identification of Biological Components and Novel Clinical Subsets of NPM1-mutated AML using an Integrated, Multi-omics Approach Christopher Oakes
42Zachary Smith
Simulations of Surface-Induced Dissociation Mass Spectrometry of a Protein Dimer Essential for Hearing Marcos Sotomayor
43Harper Smith
Modeling the open state of a mechanically activated ion channel from Arabidopsis Thaliana Marcos Sotomayor
44Diana Lopez
In Silico Analyses of Molecular Force Sensors for Mechanical Characterization of Biological Systems Carlos CastroMarcos Sotomayor
45GeunYoung Sim
Manganese-dependent microRNA trimming by 3′→5′ exonucleases generates 14-nucleotide or shorter tiny RNAs. Kotaro Nakanishi
46Moulisubhro Datta
Title not published online Venkat Gopalan
47Fawwaz Naeem
The main purpose of the anti-Shine-Dalgarno sequence of 16S rRNA in Flavobacterium johnsoniae is to enable translation of the bS21 gene Kurt Fredrick
48Isobel Bowles
A tRNA Specific Function for tRNA Methyltransferase Trm10 is associated with a new tRNA quality control mechanism in Saccharomyces cerevisiae Jane Jackman
49Lankani Gunaratne
A Surprising Role of Trypanosoma brucei La (TbLa) in controlling Queuosine levels in tRNA Juan D. Alfonzo
50Sepideh Fakhretaha Aval
Role of the sarcin-ricin loop (SRL) of 23S rRNA in assembly of the 50S ribosomal subunit Kurt Fredrick
51Aubree Zimmer
The basis of multi-step tRNA recognition by a eukaryotic tRNA editing deaminase Juan D. Alfonzo
52Paul Russell
Translation re-initiation after uORFs does not fully protect mRNAs from nonsense-mediated decay Michael G. Kearse
53Chathuri Pathirage
Human lysyl-tRNA synthetase binds to packaging-competent dimeric HIV-1 5’UTR RNA to facilitate tRNA primer placement Karin Musier-Forsyth
54Benjamin Pastore
Pre-piRNA trimming prevents piRNAs from being erroneously targets by RNA dependent RNA polymerase Wen Tang
55Brandon Iwaniec
Determining the role of the 3’-5’ reverse polymerase in Myxococcus xanthus Jane Jackman
56Talita Choudhury
Impact Of Maternal Diabetes-associated Oxidative Stress On The Developing Endocardium Vidu Garg
57Ian Price
Title not published online Wen Tang
59Debanjana Chakraborty
Title not published online Dr. Dongping Zhong
60Jamison Law
Identifying inhibitors of the FraB deglycase to design therapeutics for Salmonella-mediated gastroenteritis Venkat Gopalan
61Philip Kauffman
Title not published online Ross Dalbey
62Debasmita Mukherjee
Tomatidine targets ATF4-dependent signaling and induces ferroptosis to limit pancreatic cancer progression Thomas A. Mace
63Jillian Poska
Impact of in utero exposure to estrogenic bisphenol analogues on mammary gland development Craig J. Burd
64Anuvrat Sircar
Exploiting the Fibroblast Growth Factor Receptor-1 vulnerability to therapeutically restrict the MYC-EZH2-CDKN1C axis-driven proliferation in mantle cell lymphoma Lalit Sehgal
65Jessica Wedig
CD200R expressing myeloid cells promotes pancreatic tumor progression Thomas Mace
66Amir Yousif
Targeting epigenetic crosstalk that restrains the responses of exhausted T cells to immune checkpoint blockade therapy Hazem Ghoneim
67Jessica Nunes
Title not published online Natarajan Muthusamy
68Hannah Lovins
ChemR23 Axis Regulates Ozone-Induced Lung Inflammation and Injury Kymberly M. Gowdy
69Ariana Shannon
Generating fit-for-purpose targeted mass-spectrometry based proteomics assays from a global proteome catalog. Brian Searle
70Wantong Li
Epigenetic Regulation of Protein Kinase C Expression in the Hematopoietic Niche Bradley W Blaser
71Weiwei Liu
Identifying tumor intrinsic epigenetic regulators of MHC-I in overcoming resistance to immune checkpoint blockade Zihai Li
72Siddhi Paudel
Title not published online Timothy P. Cripe
73Junyan Yu
Designer exosome vesicles as a non-viral delivery system for neurofibromatosis type 1 (NF1) treatment Daniel Gallego-Perez Natalia Higuita-Castro
74Ashley Francois
Title not published online Matthew Stratton
75Liv Taylor
Inhibitors of Differentiation (Ids) Regulate the Timing of Cell-Cycle Exit in Muller Glia-Derived Progenitors Andy Fischer
76Anthony Alfredo
Spinal cord injury causes visceral adipose tissue inflammation and lipolysis Dana McTigue
77Kristen Pechacek
Microglia turnover at 14 days post injury fails to recover traumatic brain injury-induced impulsivity and inattention Cole Vonder Haar
78Nikaela Losievski
The role of SRP54 in motor neuron development and implications for SMA Stephen J. Kolb MD PhD
79Michaela Breach
Early life adversity changes the developing rat hippocampal transcriptome and increases later life exploratory behavior Kathryn M. Lenz
80Jonathan Packer
Title not published online Jonathan Godbout
81Ethan Goodman
Interleukin-1 receptor on glutamatergic neurons facilitates stress-induced fear responses Dr. Sheridan Dr. Godbout
82Lynde Wangler
Amplified gliosis and interferon-associated inflammation in the aging brain following diffuse traumatic brain injury Jonathan P. Godbout
83Courtney Dye
Microglia depletion facilitates the display of maternal behavior and alters activation of the maternal brain network in nulliparous female rats Kathryn M. Lenz and Benedetta Leuner
84Midhun Anne
Delineating neuronal circuits contributing to seizures and motor comorbidities in a mouse model of SCN8A DEE Jacy L. Wagnon
85Cora L. Petersen
Role of Autotaxin in CNS Autoimmunity Amy E. Lovett-Racke
86Athena Howell
Altered neural processing during self-evaluation in depression Dr. Jay Fournier
87Gargi Mishra
Title not published online Kristy L. Townsend
88Cameron Ford
Acid Sensing Ion Channels and Mitochondrial Function Candice Askwith
89Emma Woodward
Impact of Pubertal Ovarian Hormones on PV+ Interneuron Maturation in Stress-Sensitive Brain Regions Laurence Coutellier
90Meretta Hanson
Satb2 expression in CA1 hippocampal pyramidal cells is necessary for the development of feedforward inhibitory circuits Jason C. Wester
91Ileanexis Rosado-Burgos
Glutamate Transport Through Excitatory Amino Acid Transporter 1 is Essential for Neural Stem Cell Proliferation, Maintenance and Neurogenesis Liz Kirby
92Lindsay Strehle
Investigation of brain-specific estradiol supplementation for attenuation of mammary tumor-induced fatigue in a female mouse model Leah M. Pyter
93Kaarthik Abhinav Balakrishnan
Characterizing larval zebrafish behavior in thermal environments on longer timescales Martin Haesemeyer
94Chao Sun
Title not published online Chen Gu
95Shakeera Walker
Characterizing sex-specific central and peripheral immune function following paternal deprivation in vigilant-avoidant adult California mice (Peromyscus californicus) Dr. Erica Glasper
96Jessica Herstine
Astrocyte-targeted gene therapy demonstrates efficacy in two murine models of Vanishing White Matter disease Allison Bradbury
97Samuel Houle
Post injury sleep fragmentation stress increases neuroinflammatory response and impairs behavioral recovery Olga N. Kokiko-Cochran
98Ben Seicol
Inactivation of Cochlear Macrophages by Minocycline Ameliorates Noise Induced Hearing Loss in CBA/CaJ Mice Ruili Xie
99Christopher Cotter
Apoe4/Trem2R47H Behavioral Phenotyping Reveals Genotype-Dependent Impairments in Spatial Memory and Associative Learning following Traumatic Brain Injury Dr. Olga Kokiko-Cochran
100Joe Kanlong
Title not published online Karin Musier-Forsyth
101Kyle Ernzen
The PRMT5 Inhibitor EPZ015666 Demonstrates Efficacy against HTLV-1 T-cell Lines in vitro and in vivo Amanda R. Panfil
102Christina Ross
Site-specific identification of m6A RNA modification in HIV-1 genomic RNA 5'UTR Karin Musier-Forsyth
103Ezgi Elmas
Discovering novel pathways to overcome immunosuppression in NK cells Against High-grade Gliomas Dean A. Lee
104Chetan Gomatam
Dissecting the role of mineralocorticoid receptor signaling on fibrosis in dystrophic skeletal muscle Jill A. Rafael-Fortney
105Zihao Liu
Quorum sensing of Pseudomonas aeruginosa suppresses host mecrophage necroptosis during infection Haitao Wen
106Mia Kordowski
Functionalized Engineered Extracellular Vesicles for targeted delivery to Interverbal Disc Cells Natalia Higuita-Castro
107Yin Wei
Building DNA origami probe from custom scaffold for nucleosome arrays and transcripts Carlos Castro
108Archie Bhullar
Voltage controlled shutter regulates channel size and motion direction of protein aperture as durable nano-electric rectifier Dr Peixuan Guo
109Jack Kucinski
Understanding the initial in vivo activities of the fusion-oncogene PAX3-FOXO1 Genevieve Kendall
110Kristin Chesnutt
ATAC and SAGA histone acetyltransferase modules facilitate transcription factor binding to nucleosomes in an acetylation independent manner Michael G. Poirier
111Lex Tallan
Epigenetic Comparisons of PAX-FOXO1 Fusion Oncoproteins in Rhabdomyosarcoma Benjamin Stanton
112Zhiyuan Meng
Determine how pioneer transcription factors recognize and regulate nucleosomes dynamics Michael Poirier
113Julian Aldana
Comprehensive multi-omics analysis of EZH2 mutant-driven epigenetic reprogramming effects in hematologic cancer model Michael A. Freitas
114Haosheng Wen
A Curated AlphaFold 2 / AlphaFill Cadherinosome Marcos Sotomayor
115Jonathan Montgomery
Mechanism of Selective DNA Binding by Cre Recombinase Mark P. Foster
116Alina Yerbulekova
Metal-thiolate bonds in nature: Exploring covalency in a model nickel metalloprotein Hannah Shafaat
117Rachel Lew
Defining the role of NRAS mutant-specific effector interactions in cancer initiation Christin Burd
118Sabat Gonzalez-Serrano
Bioprocess development for purification of human glutamyl-prolyl-tRNA synthetase (EPRS) David Wood
119Jacelyn Greenwald
Proteomics of adipose tissue-derived extracellular vesicles from bariatric surgery patients Vicki Wysocki
120Jaylen Taylor
Bile Inhibits Bacterial Toxin Activity by Instigating Structural Destabilization and Oxidation Dmitri Kudryashov
121Md. Siddik Alom
Protein bL38 facilitates uL6 incorporation during 50S subunit assembly in the Bacteroidia Kurt L. Fredrick