Poster abstracts

Poster number 16 submitted by Malithi Jayasinghe

Reverse (3'-5') RNA polymerases: Applications beyond tRNAHis maturation

Malithi I. Jayasinghe (The Ohio State University), Krisna J. Patel (The Ohio State University)

Abstract:
Redacted abstract

References:
[1] Gu, W., Jackman, J. E., Lohan, A. J., Gray, M. W., and Phizicky, E. M. (2003) tRNA[His] maturation: An essential yeast protein catalyzes addition of a guanine nucleotide to the 5' end of tRNA[His], Genes & Development 17, 2889-2901.
[2] Jackman, J. E., and Phizicky, E. M. (2006) tRNAHis guanylyltransferase catalyzes a 3'-5' polymerization reaction that is distinct from G-1 addition, Proceedings of the National Academy of Sciences of the United States of America 103, 8640-8645.
[3] Rao, B. S., Maris, E. L., and Jackman, J. E. (2011) tRNA 5'-end repair activities of tRNA(His) guanylyltransferase (Thg1)-like proteins from Bacteria and Archaea, Nucleic Acids Research 39, 1833-1842.
[4] Long, Y. C., Abad, M. G., Olson, E. D., Carrillo, E. Y., and Jackman, J. E. (2016) Identification of distinct biological functions for four 3'-5' RNA polymerases, Nucleic Acids Research 44, 8395-8406

Keywords: Reverse (3-5) RNA polymerase, 5-end labeling, Applications